| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1384257 | Carbohydrate Research | 2012 | 5 Pages |
Abstract
Glycosylations employing 2-allylphenyl glycoside, a new type of stable glycosyl donor, were optimized and explored with a variety of acceptors promoted by ICl/AgOTf. The utility of the protocol was further demonstrated with an efficient synthesis of the disaccharide fragment of bleomycins.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► 2-Allylphenyl glycoside is herein introduced as a new type of stable glycosyl donor. ► The optimum promoter identified for this donor is the ICl/AgOTf combination. ► Alpha-mannosylations of sugar acceptors and other alcohols were demonstrated. ► The protocol was also applied in the assembly of the bleomycin sugar fragment.
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Authors
Shun-Yuan Luo, Ashish Tripathi, Medel Manuel L. Zulueta, Shang-Cheng Hung,