| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1384402 | Carbohydrate Research | 2011 | 4 Pages |
The stereoselectivity of a 2-azido-2-deoxygalactosyl (GalN3) donor is found to strongly depend on the nature of the acceptors in glycosylation reactions. The order of the acceptor, the stereochemistry, and the configuration of the monosaccharide all affect the stereochemistry outcome. More reactive acceptors are observed to favor β-products, while less reactive acceptors afford more α-products.
Graphical abstractThe stereoselectivity of a 2-azido-2-deoxygalactosyl (GalN3) donor is found to strongly depend on the nature of the acceptors in glycosylation reactions. The order of the acceptor, the stereochemistry, and the configuration of the monosaccharide all affect the stereochemistry outcome. More reactive acceptors are observed to favor β-products, while less reactive acceptors afford more α-products.Figure optionsDownload full-size imageDownload as PowerPoint slide
