| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1384406 | Carbohydrate Research | 2011 | 8 Pages |
Abstract
The naturally derived trisaccharide steroidal saponin 1 and structurally modified derivatives 2 and 3 bearing the same sarsasapogenin aglycon were synthesized concisely via a direct transglycosylation strategy. The antitumor activities of the synthetic trisaccharide saponins 1–3 and their corresponding α-isomers 1a–3a were preliminarily evaluated against human gastric adenocarcinoma cell (MKN-45) and human epithelial cervical cancer cell (HeLa) by CCK-8 assay.
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Related Topics
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Organic Chemistry
Authors
Guofeng Gu, Min Fang, Jun Liu, Li Gu,