| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1384437 | Carbohydrate Polymers | 2010 | 8 Pages |
Abstract
An immunoenhancing polysaccharide (M.W. ∼ 2.0 × 102 kDa) isolated from the aqueous extract of the leaves of Catharanthus rosea was found to consist of 6-O-methyl-glucose, arabinose, rhamnose, and methyl galacturonate with a molar ratio of nearly 1:2:1:2. On the basis of acid hydrolysis, methylation analysis, periodate oxidation, NMR experiments (1H, 13C, TOCSY, DQF-COSY, NOESY, ROESY, HMQC, and HMBC), the structure of the repeating unit of the polysaccharide was established asFigure optionsDownload full-size imageDownload as PowerPoint slideThis polysaccharide showed optimum activation of macrophages at 100 μg/mL and both splenocyte and thymocyte at 50 μg/mL, respectively.
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Authors
Sukesh Patra, Kankan K. Maity, Sanjoy K. Bhunia, Biswajit Dey, Debsankar Das, Soumitra Mondal, Bibhas Bhunia, Tapas K. Maiti, Syed. S. Islam,