| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1384639 | Carbohydrate Research | 2010 | 11 Pages |
Abstract
The synthesis of a new series of acyclic triazoloquinoxalinyl C-nucleosides and their transformation to their cyclic analogs are described following protection, activation, and deprotection with subsequent intramolecular nucleophilic substitution protocol. The antibacterial potency of the new compounds was determined using an inhibition zone diameter test. The results show that 3a and 2b exhibit good activity against Escherichiacoli and Candidaalbicans. On the other hand, the cyclic mesylated C-nucleoside 13 showed activity against the Gram-positive bacteria (Staphylococcusaureus) and antifungal activity against C. albicans.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Adel Amer, Mohammed Salah Ayoup, Sherine Nabil Khattab, Seham Yassen Hassan, Vratislav Langer, Samir Senior, Abdel Moneim El Massry,