Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1384878 | Carbohydrate Research | 2009 | 6 Pages |
Abstract
A series of novel ribavirin hydrazone derivatives were synthesized by the reaction of ribavirin hydrazone with benzaldehyde or acetophenone derivatives. The structures of the compounds were determined by IR, 1H NMR, and HRESIMS. Preliminary biological evaluation showed that one compound (7h) inhibits the growth of A549 cells at 20 μM.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Wei-Yong Liu, Hai-Ying Li, Bao-Xiang Zhao, Dong-Soo Shin, Song Lian, Jun-Ying Miao,