| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1384973 | Carbohydrate Polymers | 2012 | 9 Pages |
Amine-terminated poly(amido amine) (PAMAM) dendrimers have been attached to sodium hyaluronates (NaHAs) by a coupling reaction. The morphology of NaHAs was varied from the common network to the bead & string network, which gave rise to the decrease in viscosity of NaHAs. The bead & string network was more abundant for the covalent network complex than the noncovalent one. The beads, that is, the nano-knots of the network consist of the covalent-bonded NaHA/dendrimer composites, and the strings are NaHA chains. Beads became small and strings decreased in number with decreasing a molecular weight of NaHA. The complexation of sodium poly-l-glutamates (NaPGAs) with PAMAM dendrimers was different in the manner from that of NaHAs with dendrimers. Flexible NaPGAs produced globular composites with dendrimers.
► Amine-terminated poly(amido amine) (PAMAM) dendrimers are attached to sodium hyaluronates (NaHAs) by a coupling reaction. ► The morphology of NaHAs is varied from common network to bead & string network. ► The beads, that is, the nano-knots of the network consist of covalent-bonded NaHA/dendrimer composites, and the strings are NaHA chains.
