Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1385202 | Carbohydrate Polymers | 2006 | 8 Pages |
Abstract
Depolymerization of the sulfated galactan from Schizymenia binderi with H2O2 in the presence of copper (II) acetate afforded a homogeneous fraction (MW 8500) in 50% yield. Alkylation and NMR spectroscopy analysis of this fraction indicated the presence of an agaran–carrageenan hybrid polysaccharide composed of 3-linked β-d-galactopyranosyl residue partially sulfated at position O-2 and 4-linked α-d-galactopyranosyl and α-l-galactopyranosyl residues mainly sulfated at position O-3 and glycosylated at position O-2. Discreet anticoagulant activity, similar to that of the native polysaccharide was found in the derivative obtained by sulfation of this fraction.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Elisa A. Zúñiga, Betty Matsuhiro, Enrique Mejías,