Article ID Journal Published Year Pages File Type
1385457 Carbohydrate Polymers 2010 6 Pages PDF
Abstract

Six chemical sulfated polysaccharide derivatives (PFP-S) with variable degree of substitution (DS) and molecular weights (Mw) were prepared from the fresh persimmon fruits by chlorosulfonic acid-pyridine and ultrasonic degradation methods, and the effectiveness of the reaction was monitored by the DS, FT-IR and ζ-potential analysis. The sulfation modification might cause advanced structure change to the samples, the SEM of PFP-S exhibited a polyphasic convoluted structure. Results of anticoagulant activities showed that PFP-S could prolong activated partial thromboplastin time (APTT) and thrombin time (TT), but not prothrombin time (PT), and the anticoagulant activity improved with the increasing DS and decreasing Mw.

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
, , , , , ,