| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1385478 | Carbohydrate Research | 2007 | 7 Pages |
Abstract
The direct oxidation of UDP-α-d-glucose and UDP-N-acetyl-α-d-glucosamine to the corresponding uronic acids was explored using either TEMPO or platinum-catalysed oxidation with molecular oxygen. Whilst TEMPO-based procedures gave rise to substantial over-oxidation and/or degradation of UDP-glucose, oxidation of UDP-N-acetyl-glucosamine to UDP-N-acetyl-glucosaminuronic acid was achieved with >90% conversion and ca. 65% isolated yield using a platinum-catalysed procedure.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Martin Rejzek, Balaram Mukhopadhyay, Cory Q. Wenzel, Joseph S. Lam, Robert A. Field,