| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1387761 | Carbohydrate Research | 2015 | 9 Pages |
•Progress and recent achievements in the synthesis of glycoconjugates.•Emerging technologies that hold great promise in glycoconjugate synthesis and design.•Potential uses of glycoconjugates as therapeutics.•Chemoselective, stereoselective and regioselective manipulations of carbohydrates.•Interdisciplinary nature of modern carbohydrate research.
The ubiquity of glycoconjugates in nature and their role in different biological processes, has led to the development of several methodologies to synthesize these molecules. Synthetic glycoconjugates are now used to answer a variety of glycoconjugate-related biological questions and have provided new potential vaccines against cancer, viral, and bacterial infections and new biotechnological tools. This review aims to collect and compile the recent advances in the field of glycopeptides, glycoproteins, and glycolipid synthesis and also to update the previous reviews made on this subject. Finally, by highlighting the successes and failures of past research, we hope that this review will inspire fruitful research in this important medicinal chemistry field.
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