Recent developments in β-C-glycosides: synthesis and applications

•C-Glycosides often rely on green chemistry and facile methodology for their synthesis.•Snapshot on different methodology available for C-glycoside synthesis has been discussed.•Glycosides are commonly used as pharmacophores, biomaterials and green surfactants.•C-Glycosides are considered to be best alternatives for O-, N-, S-glycosides.•Other applications of C-glycoside are biomolecules, green surfactants and self-assembled soft-materials.

In the last few years, considerable progress has been made in the synthesis of C-glycosides. Despite its challenging chemistry, due to its versatility, C-glycosides play a pivotal role in developing novel materials, surfactants and bioactive molecules. In this review, we present snapshots of various synthetic methodologies developed for C-glycosides in the recent years and the potential application of C-glycosides derived from β-C-glycosidic ketones.

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