Article ID Journal Published Year Pages File Type
1387804 Carbohydrate Research 2012 5 Pages PDF
Abstract

Three novel lignan glycosides, 1-[4-(β-glucopyranosyl (1→2)-[β-glucopyranosyl (1→6)]-β-glucopyranosyloxy)-3-methoxyphenyl]-2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-1,3-propanediol (1), 2,3-dihydro-2-[4-(β-glucopyranosyl (1→2)-[β-glucopyranosyl (1→6)]-β-glucopyranosyloxy)-3-methoxyphenyl]-3-(hydroxymethyl)-7-methoxy-5-benzofuranpropanol (2), 7-hydroxy-9′-β-glucopyranosyloxyl secoisolariciresinol (3) and two known lignans were isolated from exocarp of Castanea henryi. Their structures were established by spectroscopic means, and their tyrosinase inhibitory potentials were evaluated in vitro using mushroom tyrosinase.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Three new lignan glycosides were isolated from exocarp of Castanea henryi. ► New lignan glycoside 2 showed most potent tyrosinase inhibitory activity. ► Known glucosides 4 and 5 exhibited inhibition against tyrosinase.

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Physical Sciences and Engineering Chemistry Organic Chemistry
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