| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1387819 | Carbohydrate Research | 2012 | 9 Pages |
Blood group A tetrasaccharides of different types have the same terminal trisaccharide fragment that allows using a block scheme in their synthesis. 3-Aminopropyl glycosides of tetrasaccharides GalNAcα1-3(Fucα1-2)Galβ1-3GlcNAcβ (A type 1), GalNAcα1-3(Fucα1-2)Galβ1-3GalNAcα (A type 3), and GalNAcα1-3(Fucα1-2)Galβ1-3GalNAcβ (A type 4) were synthesised using acetylated Galα1-3(Fucα1-2)Gal trichloroacetimidate as a glycosyl donor at the key stage.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Trichloroacetimidate of peracetylated A trisaccharide as glycosyl donor. ► Synthesis of 3-aminopropyl glycoside of A (type 1) tetrasaccharide. ► Synthesis of 3-aminopropyl glycosides of A (type 3) and A (type 4) tetrasaccharides.
