Article ID Journal Published Year Pages File Type
1387895 Carbohydrate Research 2014 8 Pages PDF
Abstract

•Key intermediate 9 was prepared from d-(−)-isoascorbic acid as well as d-ribose.•Bio-active compounds 1, 4, and 5 were obtained from a common intermediate 18.•Grubbs RCM, Morita–Baylis–Hillman (MBH), and Luche reductions are key steps.

Asymmetric total synthesis of (+)-gabosine C, (+)-pericosine B, and (+)-pericosine C has been reported from readily available d-(−)-isoascorbic acid and d-ribose involving Grubbs ring closing metathesis, Morita–Baylis–Hillman (MBH) reaction, and Luche reduction.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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