Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1387938 | Carbohydrate Research | 2010 | 18 Pages |
Abstract
The ABO histo-blood group system is one of the most clinically important antigen families. As part of our overall goal to prepare the entire set of the A, B and H type I–VI antigens for a range of biochemical investigations, we report herein the synthesis of the type I and II antigens with a 7-octen-1-yl aglycone. This linker was chosen to facilitate not only the future conjugation of the antigens to a protein or solid support but also the synthesis of the H type I and II octyl glycosides for enzyme kinetic studies.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Peter J. Meloncelli, Todd L. Lowary,