| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1388358 | Carbohydrate Research | 2009 | 6 Pages |
Abstract
A series of potential UDP-sugar mimics were readily synthesised by copper(I) catalysed modified Huisgen cycloaddition of the corresponding α-propargyl glycosides with 5-azido uridine in aqueous solution. None of the compounds accessed displayed significant inhibitory activity at concentrations of up to 4.5 mM in an assay against bovine milk β-1,4-galactosyltransferase.
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Authors
Kar Kheng Yeoh, Terry D. Butters, Brendan L. Wilkinson, Antony J. Fairbanks,