| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1388390 | Carbohydrate Research | 2011 | 5 Pages |
Abstract
1,2-cis-Glycosyl acetates with the α-configuration were revealed to be very unreactive towards Lewis acid catalyzed thioglycosylations. Optimal and cost-effective conditions for enabling this direct conversion is absent in the literature. Our studies have shown that elevating the reaction temperature with a catalytic amount of BF3·OEt2 was more effective than changing Lewis acids with higher acidities to accommodate the low reactivity of α-glycosyl acetates. The effect of impurities in stored BF3·OEt2 on the reaction is also discussed.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ci Xu, Han Liu, Xuechen Li,