Fluorous-based carbohydrate Quartz Crystal Microbalance

•The first fluorous Quartz Crystal Microbalance was prepared.•Carbohydrate–protein interaction and carbohydrate–carbohydrate interaction were successfully measured.•ΔD was employed to differentiate specific interactions from non-specific ones.

Fluorous chemistry has brought many applications from catalysis to separation science, from supramolecular materials to analytical chemistry. However, fluorous-based Quartz Crystal Microbalance (QCM) has not been reported so far. In the current paper, fluorous interaction has been firstly utilized in QCM, and carbohydrate–protein interaction and carbohydrate–carbohydrate interaction have been detected afterward.Figure optionsDownload full-size imageDownload as PowerPoint slide

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