Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1388422 | Carbohydrate Research | 2008 | 7 Pages |
Abstract
The sialyl Lewis x tetrasaccharide with a propylamine aglycon was assembled by chemoselective glycosylation from a p-tolyl thioglycosyl donor obtained from an enzymatically synthesized sialodisaccharide. Combining the advantages of highly efficient enzymatic synthesis of sialoside building blocks, and diverse chemical glycosylation, this chemoenzymatic approach is practical for obtaining complex sialosides and their analogues.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hongzhi Cao, Shengshu Huang, Jiansong Cheng, Yanhong Li, Saddam Muthana, Bryan Son, Xi Chen,