| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1388475 | Carbohydrate Research | 2015 | 6 Pages |
Abstract
•Chemical synthesis of unsymmetrical 3,6-branched Man5 oligosaccharide.•One-pot sequential glycosylation is superior to stepwise synthesis.•Three-component convergent synthesis.
An expeditious three-component, one-pot sequential glycosylation protocol has been developed for the preparation of 3,6-branched unsymmetrical mannopentaose (Man5), employing a mannose trisaccharide donor, a mannose monosaccharide donor and a mannose monosaccharide acceptor. The high efficiency of this one-pot procedure was demonstrated by comparison study with a stepwise synthesis using the same three building blocks.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yan Zhang, Congcong Chen, Lan Jin, Haining Tan, Fengshan Wang, Hongzhi Cao,