| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1388694 | Carbohydrate Research | 2008 | 7 Pages |
Abstract
The full structure of the long- and short-chain O-antigen of Yersinia pseudotuberculosis O:2a containing two uncommon deoxy sugars, abequose and 6-deoxy-d-manno-heptose (6dmanHep), was established, for the first time, by sugar analysis, NMR spectroscopy, and high-resolution ESIMS. Similar structural studies were also performed on two O:2a mutants with single disruption of 6dmanHep synthesis pathway genes each, which synthesize modified long-chain (dmhA mutant) and short-chain (both dmhA and dmhB mutants) O-antigens with 6dmanHep replaced by its putative biosynthetic precursor, d-glycero-d-manno-heptose.
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Authors
Anna N. Kondakova, Nathan Ho, Olga V. Bystrova, Alexander S. Shashkov, Buko Lindner, Carole Creuzenet, Yuriy A. Knirel,