| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1388911 | Carbohydrate Research | 2007 | 8 Pages |
Abstract
A facile and efficient methodology has been developed for the synthesis of dithymidine and di-uridine derived disulfides using benzyltriethylammonium tetrathiomolybdate as a sulfur transfer reagent. However, a similar reaction of thymidine derivative with tetraethylammonium tetraselenotungstate as a selenium transfer reagent resulted in the formation of an unexpected cyclic diselenide. The disulfide derivatives of nucleosides have been used as precursors in a tandem disulfide cleavage-Michael addition/ring opening reactions to construct aminoacid and carbocyclic derivatives of nucleosides.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kirubakaran Sivapriya, Perumal Suguna, S. Shubashree, Perali Ramu Sridhar, Srinivasan Chandrasekaran,