| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1389046 | Carbohydrate Research | 2008 | 4 Pages |
Abstract
An efficient method for the large-scale preparation of α-N-acetylglycosaminides, such as fluorogenic TN-antigen probes and an α-GalNAc-Ser derivative, has been achieved using FeCl3-catalyzed one-step condensation between commercially available d-glycosamine pentaacetates and fluorogenic acceptors (or serine acceptor) in refluxing 1,2-dichloroethane. Experimental simplicity, high α-stereoselectivity, low cost, satisfactory yield, and the environmentally benign nature are major advantages of our approach.
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Related Topics
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Chemistry
Organic Chemistry
Authors
Guohua Wei, Xun Lv, Yuguo Du,