| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1389198 | Carbohydrate Research | 2011 | 7 Pages |
A facile microwave-induced method was developed for synthesizing water-soluble fluorescent derivatives of alginic acid (ALG) with four different diamines, hydrazine (HY), ethylenediamine (EDA), 1,6-hexanediamine (HDA), and 1,4-cyclohexanediamine (CHDA), followed by a cross-linking reaction with a natural cross linker genipin. The ethylenediamine derivative of alginic acid (ALG-EDA) exhibited good fluorescent activity, which upon cross linking was enhanced threefold. The other amide derivatives, for example, ALG-HY, ALG-HDA, and ALG-CHDA, were not fluorescent, but their respective crosslinked products exhibited excellent fluorescent activity. The fluorescence intensity had an inverse correlation with the number of carbon atoms present in the amine, which in turn was a function of degree of substitution (DS). These fluorescent polysaccharide derivatives are of potential utility in the domain of sensor applications.
Graphical abstractA microwave induced facile method to synthesize water soluble fluorescent alginic acid amides and their cross linked products with a natural crosslinker genipin is described.Figure optionsDownload full-size imageDownload as PowerPoint slide
