Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1389244 | Carbohydrate Research | 2007 | 6 Pages |
Abstract
The preparation of 6,6,1′,1′,6′,6′-hexadeutero sucrose is reported. The synthesis is based on a triple oxidation of a protected sucrose 6,1′,6′-triol to the corresponding 6,1′,6′-tricarboxylic acid or ester, followed by reduction with lithium aluminium deuteride. This triple oxidation could be achieved either using cat. TEMPO–NaOCl (to the acid) or PDC–Ac2O–t-BuOH (to the t-butyl carboxylic ester).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Marie-Hélène Gouy, Mathieu Danel, Maud Gayral, Alain Bouchu, Yves Queneau,