Total synthesis of phenylpropanoid glycosides, grayanoside A and syringalide B, through a common intermediate

Phenylpropanoid glycosides are known as bioactive natural products. Two of them, grayanoside A (1) and syringalide B (2), were synthesized through a common intermediate, using benzyl as temporary protecting group following a shorter route.

Graphical abstractTwo phenylpropanoid glycosides namely, grayanoside A (1) and syringalide B (2), were synthesized through a common intermediate, using benzyl as temporary protecting group following a shorter route.Figure optionsDownload full-size imageDownload as PowerPoint slide