| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1389308 | Carbohydrate Research | 2007 | 8 Pages |
Abstract
The interaction between (−)-epigallocatechin-3-gallate (EGCG) and β- or γ-cyclodextrin (CD), in free solution and bonded to silica beads, has been studied by 1H HR-MAS NMR spectroscopy. The chromatographic retardation of EGCG on columns packed with CD-silica beads was shown to be due to the interaction of EGCG with the CD ligands because no nonspecific interaction with the silica gel could be observed. EGCG forms a tighter complex with β-CD than with γ-CD and NMR data obtained from hydroxy protons together with mm2 calculations suggest that for β-CD intermolecular hydrogen bonding, in addition to hydrophobic interaction, stabilizes the complex.
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Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Jun Xu, Tianwei Tan, Jan-Christer Janson, Lennart Kenne, Corine Sandström,