| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1389424 | Carbohydrate Research | 2009 | 7 Pages |
Abstract
Direct conversion of peracylated N1-(β-d-glucopyranosyl)-2-thiouracil derivatives into the corresponding anhydrothionucleosides has been studied under various conditions including: gas-phase pyrolysis, heating without a solvent, and by heating in a solvent of high boiling point (DPE) in the presence of a base (DABCO) and reaction in a microwave reactor. Heating at 210–220 °C was found to give the best yield of a single isomer. The structures of the new anhydrothionucleosides were confirmed by NMR techniques.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nouria A. Al-Awadi, Yehia A. Ibrahim, Maher R. Ibrahim,