Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1389450 | Carbohydrate Research | 2006 | 13 Pages |
Abstract
A direct and general access to d-glycosyl 3-, 5-, or 6-methylenediphosphonates, di-d-glycosyl 1,5-, 3,5-, 3,6-, 5,5-, or 6,6-methylenediphosphonates and dithymidine 3′,5′-methylenediphosphonate is described. The method involves the one-pot alkylidenediphosphorylation of glycosyl or thymidine derivatives. No antiviral activity was detected against a panel of RNA and DNA viruses.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Claude Grison, Stéphane Joliez, E. De Clercq, Philippe Coutrot,