Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1389464 | Carbohydrate Research | 2009 | 6 Pages |
Abstract
3-Acetamido-5-amino-3,5,6-trideoxy-d-glucono-1,5-lactam and 3-acetamido-5-amino-3,5-dideoxy-d-glucono-1,5-lactam were synthesized from corresponding 3-acetamido-3-deoxy-β-d-glucopyranosides in 63% and 35% overall yield, respectively. Acetylation followed by reduction led to the title 3-acetamido-3-deoxy derivatives of both deoxynojirimycin and 1,6-dideoxynojirimycin. The procedure developed is useful for a multi-gram scale.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ondřej Šimák, Jan Staněk, Jitka Moravcová,