Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1389650 | Carbohydrate Research | 2008 | 8 Pages |
Abstract
A novel one-step method of preparing polysubstituted guanidinoglucosides using peracetylated methyl 6-deoxy-6-thioureidoglucosides as starting materials and employing HgO in combination with molecular sieves as an efficient catalyst is reported. The structures of three methyl 2,3,4-tri-O-acetyl-6-[N2-(benzothiazol-2-yl)-N3-(oxydi-1,2-ethandiyl)]guanidino-6-deoxy-α-d-glucopyranosides were unambiguously confirmed by X-ray crystallography. The methodology affords new compounds in good yields and also provides a promising route for the synthesis of carbamate-protected guanidines.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yong-Hua Liu, Ling-Hua Cao,