| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1389663 | Carbohydrate Research | 2008 | 4 Pages |
Abstract
Methyl 5-N-acetyl-7-O-acetyl-4-azido-2,3-didehydro-2,4-dideoxy-neuraminic acid (4azido-Neu2en5,7 Ac21Me) was synthesized regioselectively starting from 4azido-Neu2en5Ac1Me in high yield. The transformation of 4azido-Neu2en5,7Ac21Me to the corresponding thermodynamically stable 4azido-Neu2en5,9Ac21Me via intramolecular acetyl migration was confirmed by single-crystal X-ray diffraction analysis. The proposed rearrangement mechanism is discussed.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Qingjie Zhao, Yuanyuan Lou, Ruisheng Xiong, Haihong Li, Jingshan Shen,