| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1389755 | Carbohydrate Research | 2008 | 5 Pages |
Abstract
The O-antigen structure of Shigella dysenteriae type 2 was reinvestigated using chemical modifications along with high-resolution 2D 1H and 13C NMR spectroscopy. The O-antigen was found to contain a pyruvic acid acetal, which was overlooked in an early study, and the following revised structure of the pentasaccharide repeating unit was established:Figure optionsDownload full-size imageDownload as PowerPoint slidewhere ∼70% GlcNAc residues bear an O-acetyl group at position 3. The O-antigen of Escherichia coli O112ac was found to have the same carbohydrate structure but to lack O-acetylation.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Andrei V. Perepelov, Andrej Weintraub, Bin Liu, Sof’ya N. Senchenkova, Alexander S. Shashkov, Lu Feng, Lei Wang, Göran Widmalm, Yuriy A. Knirel,