Article ID Journal Published Year Pages File Type
1390288 Carbohydrate Research 2013 9 Pages PDF
Abstract

•We have developed a new method to produce DMDP.•This method can give access to several analogues for structures/activities relationships.•A stereoselective reduction has been observed and rationalised.

One of the most frequently synthesized iminosugar derivatives is DMDP. Starting from l-sorbose, a practical method for the synthesis of derivatives of this five-membered iminocyclitol has been developed, involving straightforward steps and a convenient selective reduction of a ketoxime intermediate.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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