Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1390288 | Carbohydrate Research | 2013 | 9 Pages |
Abstract
•We have developed a new method to produce DMDP.•This method can give access to several analogues for structures/activities relationships.•A stereoselective reduction has been observed and rationalised.
One of the most frequently synthesized iminosugar derivatives is DMDP. Starting from l-sorbose, a practical method for the synthesis of derivatives of this five-membered iminocyclitol has been developed, involving straightforward steps and a convenient selective reduction of a ketoxime intermediate.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sébastien Balieu, Arnaud Guilleret, Romain Reynaud, Agathe Martinez, Arnaud Haudrechy,