Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1390299 | Carbohydrate Research | 2013 | 5 Pages |
•Alkylmethylimidazolium ionic liquids are non-inert solvents of cellulose.•The side reaction mechanism of [bmim]+ with glucose was studied theoretically.•The reaction involves the deprotonation of [bmim]+ and its nucleophilic addition.•The deprotonation process of [bmim]+ by TEA promotes the side reaction.
To understand the non-inert nature of ionic liquids in cellulose chemistry, density functional theory calculations were carried out to investigate the reaction of 1-butyl-3-methylimidazolium cation ([bmim]+) with model compounds α- and β-glucoses (the basic units of cellulose and its degradation products) in the absence and presence of base, triethylamine (TEA).The calculated energy barriers for the reactions of [bmim]+ with α- and β-glucoses without TEA were 67.97 and 66.19 kcal mol−1, respectively. With the assistance of TEA, the barriers were reduced to 48.17 and 46.96 kcal mol−1, due to the enhanced electrophilic abilities of H6 and nucleophilic abilities of C2 induced through deprotonation of the C2 atom, respectively. The present results rationalize the experimental finding well and provide a clear explanation on why imidazolium-based ionic liquids are considered as non-inert solvents in cellulose chemistry.
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