Article ID Journal Published Year Pages File Type
1390363 Carbohydrate Research 2012 8 Pages PDF
Abstract

Uruburuella suis is a novel species isolated from lungs and heart of pigs with pneumonia and pericarditis. Phenotypic and phylogenetic evidences showed that it represented a hitherto unknown subline within the family Neisseriaceae. In the present work we defined the whole structure of the LPS isolated from Uruburuella suis. The structural determination, which was achieved by chemical, spectroscopic and spectrometric approaches, indicates a novel rough type lipopolysaccharide rich in negatively charged groups in the lipid A-inner core region. The elucidation of the structural features of the LPS from Uruburuella suis is a first step toward the comprehension of the characteristics of the cell envelope in such new and interesting microorganisms.

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Uruburuella suis is a novel species isolated from lungs and heart of pigs with pneumonia and pericarditis. ► The lipooligosaccharide (LOS) from Uruburuella suis has been extracted and purified. ► 2D NMR and MALDI MS studies lead to the full structural characterization of the lipooligosaccharide. ► The LOS has a strong accumulation of negative charges in the lipid A-core region.

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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