| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1390381 | Carbohydrate Research | 2012 | 9 Pages |
Figure optionsDownload full-size imageDownload as PowerPoint slideN-(p-Methylphenylthio)-ε-caprolactam (1) in combination with trimethylsilyl trifluoromethanesulfonate (TMSOTf) provides an efficient thiophilic promoter system, capable of activating different thioglycosides. Both ‘armed’ and ‘disarmed’ thioglycosyl donors were activated for glycosidic bond formation. Notably, this reagent combination works well in reactivity-based one-pot oligosaccharide assembly strategy.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► N-(p-Methylphenylthio)-ε-caprolactam-TMSOTf acts as efficient activator for glycosylation reaction based on thioglycosides. ► Both armed and disarmed thioglycosyl donors are activated. ► The reagent system works well in reactivity based one-pot oligosaccharide assembly.
