Article ID Journal Published Year Pages File Type
1390418 Carbohydrate Research 2011 13 Pages PDF
Abstract

The total chemical synthesis of a Forssman antigen analog is described. The pentasaccharide contains a functionalized tether which should facilitate future conjugation with immunogenic proteins. We found that the total synthesis can be efficiently achieved by following a convergent 2+3 strategy, and using N-Troc protected GalNAc thioglycoside as a donor.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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