Article ID Journal Published Year Pages File Type
1390480 Carbohydrate Research 2011 4 Pages PDF
Abstract

Commercially available zinc dust in the presence of ammonium chloride in acetonitrile at reflux removes the 2,2,2-trichloroethyl (TCE) group at anomeric centers with excellent yields (>95%) in short reaction times. This present method is easily implemented on substrates containing acyl and benzyl groups and large-scale reactions also proceed in high yield.

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Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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