| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1390504 | Carbohydrate Research | 2011 | 4 Pages |
Abstract
Glycosyl azides undergo smooth 1,3-dipolar cycloaddition with benzyne generated in situ from 2-(trimethylsilyl)phenyltrifluoromethanesulfonate and cesium fluoride under mild conditions to furnish 1,2,3-benzotriazole-linked glycoconjugates in excellent yields and with high stereoselectivity. This method provides a novel class of benzotriazole linked glycoconjugates in a single-step reaction. This is the first example of a fluoride- triggered 1,3-dipolar cycloaddition of benzyne with glycosyl azides.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Basi V. Subba Reddy, Karanam Praneeth, Jhillu S. Yadav,