Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1390758 | Carbohydrate Research | 2008 | 7 Pages |
Abstract
β-C-Glucosyl and β-C-galactosyl-1,4-dimethoxynaphthalenes have been synthesized using a F3CCO2Ag/SnCl4 promoted Friedel–Crafts electrophilic substitution reaction. Both glycosyl acetates and methyl glycosides can be used as glycosyl donors. Further oxidation afforded the corresponding β-C-glycosyl-1,4-naphthoquinones. The in vitro cytotoxic activity of these compounds was evaluated against the A375 cell line.
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Related Topics
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Organic Chemistry
Authors
Li Lin, Xiao-Peng He, Qing Xu, Guo-Rong Chen, Juan Xie,