Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1390821 | Carbohydrate Research | 2007 | 12 Pages |
Abstract
The synthesis of a C-disaccharide that is designed as a mimetic for the repeating unit disaccharide of hyaluronic acid is described. The target compound was obtained via the SmI2-promoted coupling reaction of the sulfone, 2-acetamido-4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-1,2-dideoxy-1-pyridinylsulfonyl-β-d-glucopyranose (6), and the aldehyde, p-methoxyphenyl 2,3-di-O-benzyl-4-deoxy-4-C-formyl-6-O-p-methoxybenzyl-β-d-glucopyranoside (14).
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhong-Xu Ren, Qiang Yang, Kenneth N. Price, Tianniu Chen, Cara Nygren, John F.C. Turner, David C. Baker,