| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1390990 | Carbohydrate Research | 2006 | 6 Pages |
Abstract
Based on our extensive studies of d-glucosidase inhibiting 2,5-dideoxy-2,5-imino-d-mannitol derivatives, we have been trying to create a series of fluorescent derivatives with a view to an ‘inhibitory activity ruler’ based on competitive displacement reactions of non-fluorescent inhibitors by fluorescent ones and vice versa, which can be performed and followed in microtiter plates or on-chips. Thus, a set of compounds was assembled with Ki values between 2 nM and 1 μM against Agrobacterium sp. β-glucosidase.
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Related Topics
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Authors
Tanja M. Wrodnigg, Arnold E. Stütz, Chris A. Tarling, Stephen G. Withers,