Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1391645 | Chemistry & Biology | 2008 | 7 Pages |
Abstract
Communication through quorum sensing (QS) enables bacterial populations to coordinate their behavior. Recent work on N-acylhomoserine lactone-mediated QS has revealed that some soil bacteria exploit host-derived substrates to generate an alternative N-substituted homoserine lactone. New light has also been shed on the mechanism by which N-(3-oxo-dodecanoyl)-l-homoserine lactone modulates host inflammatory signaling pathways to promote bacterial survival.
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Authors
Margaret Cooley, Siri Ram Chhabra, Paul Williams,