| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1392079 | European Journal of Medicinal Chemistry | 2015 | 12 Pages |
Abstract
Thirty-six icaritin derivatives bearing carboxylic functions have been synthesized. Several derivatives show improved activity against cancer cells, of which 5b and 5d display high selectivity and strong potency to the ER-positive breast cancer cell line MCF-7.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Chen Wang, Ping Wu, Jing-Fang Shi, Zi-Hua Jiang, Xiao-Yi Wei,