Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer

Article ID	Journal	Published Year	Pages	File Type
1392083	European Journal of Medicinal Chemistry	2015	13 Pages	PDF

Keywords

dThd 10B RPR DEAE d4T PEI AZT TK1 PTA ATCC HRP IACUC TBDMS BNCT Thymidine kinase 1 (TK1)ICP-OES FBS DMEM Dulbecco's modified Eagle's medium siRNA LET Stavudine small interfering ribonucleic acid Linear Energy Transfer boron Boron-10 tert-butyldimethylsilyl Thymidine Thymidine kinase 1 Boron neutron capture therapy (BNCT)boron neutron capture therapy Diethylaminoethanol Zidovudine Institutional Animal Care and Use Committee fetal bovine serum Inductively coupled plasma-optical emission spectroscopy American Type Culture Collection Monophosphate Horseradish peroxidase Polyethylenimine Carborane

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Synthesis and evaluation of thymidine kinase 1-targeting carboranyl pyrimidine nucleoside analogs for boron neutron capture therapy of cancer

Authors

Hitesh K. Agarwal, Ahmed Khalil, Keisuke Ishita, Weilian Yang, Robin J. Nakkula, Lai-Chu Wu, Tehane Ali, Rohit Tiwari, Youngjoo Byun, Rolf F. Barth, Werner Tjarks,