Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1392137 | European Journal of Medicinal Chemistry | 2015 | 21 Pages |
•A didactic survey of gold nanoparticles synthesis.•Anticancer agents and targeting strategy used with gold nanoparticles are shortly presented.•The parameters for gold nanoparticles biodistribution are described.•Chemicals used to functionalize gold nanoparticles are reviewed by classes.•Principle for bioassays in oncology involving gold nanoparticles are presented.
This review presents in a comprehensive ways the chemical methods used to functionalize gold nanoparticles with focus on anti-cancer applications. The review covers the parameters required for the synthesis gold nanoparticles with defined shapes and sizes, method for targeted delivery in tumours, and selected examples of anti-cancers compounds delivered with gold nanoparticles. A short survey of bioassays for oncology based on gold nanoparticles is also presented.
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