Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1392794 | European Journal of Medicinal Chemistry | 2012 | 9 Pages |
Abstract
⺠Novel amidino substituted bis-benzothiazolyl-pyridines and pyrazine were synthesized. ⺠Their antiproliferative activity against several human cancer cell lines was determinated. ⺠Diimidazolinyl-derivatives, exerted stronger concentration-dependent antiproliferative effects. ⺠Biological studies on SW620 cell line and BJ fibroblasts revealed oxidative stress as a possible mechanism.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Livio Racané, Sandra KraljeviÄ PaveliÄ, Ivana Ratkaj, ViÅ¡nja StepaniÄ, KreÅ¡imir PaveliÄ, Vesna TraliÄ-KulenoviÄ, Grace Karminski-Zamola,