| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1393106 | European Journal of Medicinal Chemistry | 2010 | 6 Pages |
Abstract
Aminoalkyl substituted derivatives were synthesized starting from glycyrrhetinic acid methyl ester and screened for antitumor activity in a panel of 15 human cancer cell lines by an SRB assay. The most compound 7 possesses an aminohexyl side chain, induces apoptosis and shows IC50 values of 0.6–3.0 μM.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
René Csuk, Stefan Schwarz, Ralph Kluge, Dieter Ströhl,